Rodents

The rodent research at our lab focuses on multiple aspects of animal behavior related to addiction, learning and memory, anxiety, and depression. We employ a comprehensive range of behavioral tests and procedures, including:

Conditioned Place Preference (CPP) – assessing drug reward and addiction mechanisms,

Forced Swimming Test (FST) – evaluating depressive-like behavior and antidepressant effects,

Novel Object Recognition (NOR) Test – measuring memory and cognitive function,

Elevated Plus Maze (EPM) – testing anxiety-related responses,

Chronic Mild Unpredictable Stress (CMUS) Model – simulating prolonged stress exposure for depression studies.


In addition to behavioral studies, our research integrates biochemical, molecular, and histological analyses, providing a deeper understanding of underlying neurobiological mechanisms. Beyond behavioral neuroscience, we utilize rodent models for metabolic diseases and cancer research, enabling a broader exploration of disease mechanisms and potential therapies. Our work includes:

Metabolic Disease Models – investigating obesity, insulin resistance, and metabolic syndrome,

Xenograft Models – studying tumor growth and testing anticancer therapies in vivo,

Neurodegenerative Disease Models – exploring the progression of disorders such as Parkinson’s and Alzheimer’s disease.


By combining behavioral, biochemical, and molecular approaches, our research aims to enhance translational potential and contribute to the development of innovative therapeutic strategies.

Zebrafish

In our laboratory, we utilize the larval zebrafish model in:

Acute toxicity tests (ZFET) – assessing the toxic potential of various compounds,

Drug-induced cardiotoxicity tests – evaluating the effects of pharmacological agents on heart function,

Larval behavioral assays – including tests for anxiety, locomotion, and a 6-OHDA-induced Parkinson’s disease model,

Metabolic disease models – investigating metabolic disorders and their molecular mechanisms,

Cancer research (xenograft) – studying tumor development, progression, and potential therapeutic compounds.

By integrating zebrafish assays into our research, we aim to enhance the understanding of disease mechanisms and improve drug screening strategies in an efficient and ethically responsible manner.

Analytics

We have experience in quantifying amino acids and neurochemicals, assessing antioxidant parameters, and performing in vitro toxicological tests on cell lines

Drag and Drop Website Builder